Dr. Ellenbogen's Plastic Surgery Blog

How To Be Parisian: 7 French beauty tips from Caroline de Maigret

Sun, 10/19/2014

Caroline de Maigret is our new beauty crush, not just because she oozes that laissez-faire, 'I woke up like this' kind of style, but also because she's decided to write a style-guide on getting the look in her new book "How to be Parisian" which makes us like her even more.

Penned with her good friends Anne Berest, Audrey Diwan and Sophie Mas (also super cool, and of course also of that Parisian effortless beauty) model de Maigret describes what it's like to be a Parisian woman, and in true whimsical French fashion added a few beauty how-tos.

Here are our favourite French lessons in beauty.

On skin... 

French model Laetitia Casta and her pharmacy-perfect skin

- Beauty in France is epidermal - nobody cares that much about make-up, it's what's underneath that matters. 

- Skin should look natural. Freckles can appear in spring... sometimes your cheekbones blush when you lie, and your whole face flushes when you are intimidated. 

- French women avoid using foundation, which merely serves as a shroud, and therefore trivialises. 

- Skin of your face must be treated as a canvas. Start with a moisturiser to smooth your skin. 

- Hide any imperfections with concealers (such as YSL's Touch Eclat) or a BB cream. If you really can't live without your foundation, then mix it with a touch of moisturiser to mute its effect. 

- Never go to bed without taking off your make-up, so you fall asleep not smelling like the party. Yes you climb into bed more tired for this care. But that's the price we pay to save our skin.

On make-up... 

- A few strokes of mascara (Hypnôse by Lancôme) - be generous on your top and bottom lashes, to accentuate your look and disguise any bags under your eyes. 

- Bright red lipstick (Dior Addict) will not go amiss for a night out.

On hair... 

Caroline de Maigret for Whistles. Photo: @carolinedemaigret

One of the Parisienne's most distinctive features is her head of hair. There are several characteristics that make it easy to identify. Her hair style is never "immaculate" and it's rare that she goes for a blowout. She cultivates, depending on her age a type of capillary blur, to varying degrees of tidiness:

- Do not dye your hair, or if you do, only in your original colour to highlight it, or to hide any grey. 

- Do not dry your hair with a hair dryer (in fact, you might as well throw your hair dryer away) but instead use two much more environmentally friendly resources: fresh air in summer and a towel in winter. Whenever possible, wash your hair in the evening rather than in the morning, so as not to leave the house with wet hair. 

- There's no point in accessorising your hair. Avoid hair clips or headbands if you're over 18. 

- As your face gets messier with age, your hair can get neater for balance. 

- Either go all grey or no grey hair. Salt and pepper is for the table. 

- Rum, honey, two eggs yolks and the juice of a lemon: not a recipe for baba au rhum, but just what you need for a restorative hair mask.

On nails... 

Essie Nail Polish Mademoiselle, £7.99

- Short, clean nails, sometime worn with polish. 

- The French manicure is something of an enigma: it is the exact opposite of French chic. The Parisienne does not understand the point of it and never wears it. 

- She'll go to great lengths for a pedicure but wears mismatched underwear. 

- Before throwing out a juiced lemon, rub it on your fingernails - it'll strengthen and brighten them.

On plastic surgery... 

Photo: Getty

- First choose one part to focus on, one single operation. 

- Next, put off for as long as possible. In France it is rare to find a 35-year-old who has had plastic surgery. 

- Generally the fight begins in your Forties, often with the help of hyaluronic acid and Botox. 

- Resort to Botox no times than once a year, or else you run the risk of it becoming visible. 

- Small lifts are contemplated after the age of 50: your eyelids, the bags under your eyes or the wrinkles around your mouth, 

- At the age of 60, you can think about maybe getting a "mini-lift".

On health... 

Caroline de Maigret's. Photo: @carolinedemaigret

- She drinks vodka in the evening and green tea in the morning. 

- She eats a four-cheese pizza but puts Stevia in her coffee. 

- Once a week, brush your teeth wtih baking soda - it's a natural whitener. 

- Drink a gallon of water before going to sleep - it's the best way to avoid a hangover. 

- Your skin retains the memory of every party you ever went to, under your eyes and at the corners of your lips. Be wary of your excess. 

- Your skin, hair and nails all love beer. Not the kind you drink - that gives you a belly - but instead beer in the form of brewer's yeast. Sprinkle it on salads, steak and vegetables. It's an excellent alternative to salt. 

- On exercise? She thinks of her mother's backside and the cost of a gym membership, but that's not enough. 

- In short, you're not a slave to the cult of the perfect body - so learn to make the best of what nature gave you. 

- An aromatherapy massage isn't a luxury, it's an investment in well-being.

On imperfections... 

Vanessa Paradis and her oh-so Parisian gap-toothed beauty

- The Parisienne retains her little imperfections, cherishes them even (the gap in her smile or her slightly crooked tooth, her prominent eyebrows or strong nose): these are the signs of a certain strength or character and allow her to feel beautiful without being perfect. 

- The Faux Pas: over-plucking your eyebrows. Having lip augmentation - it makes you look like a duck. Wearing too much make-up. Having more than two different colours in your hair.

On perfume...

- Find your perfume before you turn thirty. Wear it for the next thirty years. 

- Be unfaithful: cheat on your perfume, but only on cold days. 

- A touch of perfume on your hair, behind your ear or on the nape of the neck, never did anyone any harm. 

- Always put on perfume before going out. 

5 Anti-Aging Steps To Take In Middle Age

Sun, 10/19/2014


When it comes to anti-aging, prevention is the best cure. Some experts say prevention begins as early as your 20s, with proper sun protection and a personalized skincare regimen. But now that we're in our 50s, it's more about maintenance than turning back the clock.

We're heard about the lengths to which people will go to preserve their youth, fromvampire and even semen facials to using bird-droppings to preserve the skin. Here are some things you can incorporate into your beauty routine that will help with your particular concerns -- things like age spots, crow's feet and wrinkles.

1. Whiten your teeth

teeth whitening

No matter how much makeup you're wearing or how great your hair looks, your smile is what catches everyone's eye. But as we age, our tooth enamel becomes worn downafter years of use, revealing a yellowing color underneath. To avoid this, make sure you cut out any habits that only make this worse. Smoking and regular coffee-drinking stains teeth.

Also, make sure you're not slacking on oral care. If you don't already floss, start. And don't skip out on your regular cleanings with the dentist. To brighten teeth further, you can use an at-home whitening kit, purchased either at the store or from your dentist, to brighten your teeth a few shades. We recommend you consult with your dentist for your best whitening option or even ask if they offer any in-office whitening treatments.

2. Start using a serum -- if you're not already

A day cream and a night cream may have been enough in your 30s and 40s, but drying, aging skin needs a little more help. Serums, with their water-like consistency, are generally soaked up by your thirsty skin a lot more than heavy creams. Adding this step to your skincare routine not only adds extra moisture, it helps deliver powerful anti-aging ingredients to help cell turnover. Dermatologists recommend using a serum with vitamin C which helps fight free radicals and boosts collagen production, helping your skin stay firm.

3. Don't neglect your lashes

mature eyelashes

Thinning, sparse lashes are often something you will experience as you get older, along with your hairline. Thick, defined lashes help make the eye stand out and make you look less tired. So if you don't already swear by mascara, consider giving it a chance. But more importantly, even if you aren't one for mascara, simply curling your lashes can help you look more bright-eyed. Makeup artist Sonia Kashuk tells More Magazine that lashes also lose their curl as we age. Kashuk recommends curling your lashes for extra volume, holding for a curl at the root and then halfway down the lash for more curl.

Too scared to use the scary-looking contraption that is the eyelash curler? There are plenty of ways to curl without a curler. HuffPost Style says you can even curl your lashes with the back of a spoon and a little mascara.

4. Exercise your neck

While you're busy worrying about your laugh lines, you might be neglecting one of the biggest giveaways of age: your neck. As a rule of thumb, make sure you're using the same products on your neck as you do on your face, including the all-important SPF.

If you want to go a step further, some yoga experts and dermatologists say neck exercises can help. They claim simple exercises can help improve blood flow, sending more oxygen to cells, giving you that glow we all seek. New York dermatologist David Bank told WomansDay that neck exercises can help tighten and lift your skin in as little as six weeks, according to what he's heard from his own patients. Bank suggests one exercise in which you tilt your head back, and bring your bottom lip up over your top lip, holding for 10 seconds and repeating 10 times.

5. Watch what you eat


No, were not suggesting you need to go on a diet. Think of your diet as part of your skincare regimen. Stay away from processed foods and go for natural foods that are rich in antioxidants that can literally help protect your skin from damage and help turn back the clock. We've written about foods that are as good as the fountain of youth. Try having eggs for breakfast once in a while. For a sweet treat opt for a piece of dark chocolate rather than a high-fat pastry. And use coconut oil for your skin and cooking.

Have any tips of your own? Tell us about them in comments.

The skin foam that can kill acne

Sun, 10/19/2014

Rubbing experimental treatment onto spots reduced number by 72 per cent in three months

  • FMX101 contains minocycline, an antibiotic long used to treat condition
  • But in tablet form it can have side effects including vertigo and diarrhoea
  • 150 trial patients suffered no ill effects and it could be sold in two years



Foam: A new acne drug trial produced no side effects, unlike those on the market (posed by model)


Foam: A new acne drug trial produced no side effects, unlike those on the market (posed by model)

A foam that’s squirted on to the skin could be a radical new treatment for acne. It contains small amounts of a drug called minocycline, an antibiotic that’s long been used to treat the condition.

The treatment works by destroying the bacteria that lead to acne breakouts. Although minocycline is effective when taken as a tablet, it can have nasty side-effects such as vertigo, dizziness, diarrhoea and mouth ulcers.

However, it’s hoped the new foam, which is gently rubbed on to spots and is absorbed within seconds, will slash the risk of adverse effects because the drug does not have to pass through the body before it reaches its target.

Early trials show the experimental foam, called FMX101, is as effective as the drug in pill form, with a once-daily application reducing the number of spots by around 72 per cent over a three-month period.

Crucially, none of the 150 patients who took part in the trial reported major side-effects.

Acne affects eight out of ten teenagers and more than half of women over 25. Hormonal changes cause the sebaceous glands in the skin to produce increased amounts of an oily substance called sebum.

Together with dead skin cells, the sebum blocks hair follicles, trapping bacteria that usually live harmlessly on the skin, where they actually help to protect against infection by a wide range of organisms.

The main bacterium involved is Propionibacterium acnes, or P. acnes, and, like others found on the skin, it needs a constant supply of oxygen to flourish.

But trapped inside the skin, rather than living harmlessly on the surface, it is starved of its normal supply and starts to attack healthy skin cells in an attempt to access the oxygen that is circulating in the blood.

Meanwhile, the immune system, sensing the body is under attack, sends out white blood cells to try to ward off the bacteria. The result is the inflammation and swelling that leads to an angry-looking spot that can become itchy and sore before eventually erupting and, in some cases, scarring the skin.

Treatment: Acne affects eight out of ten teenagers and more than half of women over 25 (posed by model)


Treatment: Acne affects eight out of ten teenagers and more than half of women over 25 (posed by model)

'It becomes really hard to love yourself': Model suffers with...

Treatment ranges from creams and gels for mild acne with no underlying inflammation, to powerful antibiotics — such as minocycline — to kill bacteria in the skin.

Israeli firm Foamix Inc developed the foam as an alternative to tablets. Unlike gels, ointments or creams, it disappears rapidly and leaves less of a sticky residue on the skin.

The foam is due to enter the final stages of clinical trials next year and could be available within two to three years.

Dr Tony Chu, consultant dermatologist at Hammersmith Hospital in London, says using foam to deliver drugs to affected areas of the skin was potentially a good idea.

But he warns: ‘Minocycline can cause unsightly pigmentation in scarred areas of the skin — even when taken as a tablet.

‘Another issue is the development of antibiotic drug resistance, which is increased if antibiotics are used on the skin.'

Ways To Prevent Skin Cancer

Sun, 10/19/2014

Skin cancer is a common problem nowadays. More skin damage is caused by aging, wrinkles, sagging, leathering and discolouration. The ultraviolet rays of the sun can cause more damage than you can imagine. There is no harm enjoying the sun. All you need to do is take a few precautions before you enjoy it. Harmful chemicals in your cosmetics and skin care products can also cause skin cancer. If you take extra care in your health regimen, you can stay protected from skin cancer. MOST COMMON CAUSES OF CANCER Signs and symptoms of skin cancer often remain unnoticed for a long time.

By the time it is diagnosed, the stage of cancer will be in an advanced condition. So, it is always better to keep an extra eye on protecting yourself from harmful habits and chemicals. There are a few things that you need to do to prevent skin cancer. Use sunscreen before you go out in the sun. You should also avoid using harmful cosmetics. Take a look at ways to prevent skin cancer. Sunscreen: Always chose a sunscreen which has an SPF (Sun Protection Factor) of more than 15. Reapply the sunscreen every 2 hours when you are outside. For your children, seek medical help before putting them in the sun for too long. Peak Hours: Avoid direct exposure to the sun, especially from noon to evening.

This is the time when the UV rays is the strongest or you could say that the UV index is 3 or more. Burn: Avoid getting burned in the sun. This is another way to prevent skin cancer. Every burn that you get increases the risk of skin cancer. Five or more sunburns double your lifetime risks. Tanning booths: Tanning is never safe, no matter where you get it, whether on the beach or in the tanning booth. Teenagers are sensitive to the UVR (ultraviolet radiation) that are emitted from the tanning booths. Cover up: Hats and clothes need to be worn when you are out in the sun.

This is yet another way on how to prevent skin cancer. Sunglasses can be used to protect your eyes. Protect your lips: You need to get the appropriate lip gloss with an SPF of 30. Normal lipsticks do not count as sunblock. Remember to use them every few hours, especially after eating. Clouds: Though it is a cloudy day, there are still chances that you can get a sunburn. Studies have shown that about 80 percent of the sun rays penetrate through the clouds, mist and fog. Sensitive skin care: Keep babies away from the sun, they have delicate skin and hence, they are more prone to getting sun burnt.

With older children, use a lot of sunscreen and clothing to help prevent the effect of the UV rays on their bodies. Check Moles: You should have a monthly check up on your moles. If you see any discolouration, change in shape or size, consult the doctor immediately. This is one of the ways on how to prevent skin cancer. Sores: Keep an eye on the sores. Make sure that they heal correctly. Also, care should be taken for skin areas that are reddish, bumpy, bleeding or itchy.

Read more at: http://www.boldsky.com/health/disorders-cure/2014/10-ways-to-prevent-skin-cancer-051702.html

Best ever skin: the benefits of a simple skincare routine

Sun, 10/19/2014

Rosie Huntington

Sharon McGlinchey is a facialist and the founder of MV Organic Skincare. Rosie Huntington-Whiteley is among her clients

Start every day with a cup of warm water and half a lemon. It's a great way to help cleanse the liver - the diets we have now put a heavy burden on it, so if you start your day by stimulating the digestion you lessen the load on the skin - which is a very important organ for elimination. When your digestion is working well you absorb nutrients more effectively too, which makes your skin better. It's such a simple thing to do, but it's incredibly effective.

Use a sun-dried clay mask regularly. Natural clay has incredible healing power and long-term cumulative health benefits. Dried clay retains its mineral content; as soon as you mix it with water it becomes active. Use clay you mix yourself - there are many preservatives in the tube ones (try my Signature Mineral Mask , £33). It cleanses underlying skin tissue - great if you've been wearing sunscreen long-term, when skin harbours toxins.

Trade your eye cream for jojoba oil. This liquid wax has a natural affinity with the body (you can eat it, put it on your skin and hair, so it's safe to use around the eyes). A sebum mimic, it's compatible with all skin types. It has a wonderful ability to regulate imbalances whether you have oily or dry skin. I use a certified organic jojoba oil, found in health-food shops. Try Organic Jojoba Oil (£10).

Be wary of SPFs. We need sunshine, but we need to be responsible. There is evidence that some sunscreen ingredients may actually accelerate the damage done by UV rays. Sunscreens can also have chemicals that are absorbed through the skin into underlying tissue and can't be released naturally. If you're in the sun, choose creams with UV reflectors such as zinc or titanium dioxide. The Environmental Working Group'swebsite has a list of safer sunscreens. But the best advice is simply to cover up and avoid sun in the middle of the day.

Don't over-exfoliate. Exfoliation doesn't just remove dead skin cells, it removes healthy cells too, leaving the skin exposed. This can cause pigmentation issues and long-term sensitivity, and puts the skin in a constant state of repair. I send clients on a "skin holiday", with just three products - my warm compress cleanser, jojoba oil moisturiser and signature mask, and that's it - for four to six weeks. Less is more wins every time.

Could compound in red wine, grapes treat acne?

Sun, 10/19/2014
New study published in the journal Dermatology and Therapy claims a compound derived from red grapes and found in red wine - resveratrol - may be an effective treatment for acne, particularly when combined with an already existing medication for the disorder.
Resveratrol's effects on acne bacteria

Researchers found that resveratrol appears to kill acne bacteria by weakening its outer membranes, as shown in the bottom images.

Image credit: UCLA

Acne affects 40-50 million Americans, and around 85% of us develop acne at some point in our lives. The condition is characterized by pimples, blocked pores and/or cysts that can appear on the face, neck, chest, back, shoulders and upper arms.

Acne can be caused overproduction of oil in the skin, blockage of hair follicles from which the oil is released, and growth of bacteria called Propionibacterium acnes in the hair follicles.

There are medications that help treat acne, such as benzoyl peroxide - an oxidant that produces free radicals that kill P. acnes bacteria.

But the researchers of this latest study - including first author Dr. Emma Taylor of the division of dermatology at the David Geffen School of Medicine, the University of California-Los Angeles - note that this medication can sometimes cause skin irritation, such as redness, itching and peeling skin.

Past research has indicated that resveratrol - an antioxidant found naturally in red grapes that prevents free radicals from forming - may be effective against acne, but the mechanisms behind this have been unclear. Dr. Taylor and colleagues set out to investigate.

A 'two-pronged attack' on acne bacteria

The team applied resveratrol, benzoyl peroxide, and a combination of both compounds to colonies of P. acnesbacteria, and assessed their antibacterial effects for 10 days. They also cultured human skin cells and blood cells with the compounds.

They found that all concentrations of benzoyl peroxide were able to kill P. acnes, but this effect lasted no longer than 24 hours.

Resveratrol, however, appeared to kill P. acnes by weakening the outer membrane of the bacteria. Such effects lasted for 48 hours, although a concentration of at least 50 ug/mL was required.

But the team says they were surprised to find that the strongest effect against acne occurred when both resveratrol and benzoyl peroxide were combined. Not only did this combination kill bacteria at all concentrations, but the effects lasted longer.

"It was like combining the best of both worlds and offering a two-pronged attack on the bacteria," says senior author Dr. Jenny Kim, also of the division of dermatology at the Geffen School.

Commenting on the findings, Dr. Taylor says:

"We initially thought that since actions of the two compounds are opposing, the combination should cancel the other out, but they didn't.

This study demonstrates that combining an oxidant and an antioxidant may enhance each other and help sustain bacteria-fighting activity over a longer period of time."

Potential for new acne treatments

From culturing human skin cells and blood cells with the compounds, the team also found that benzoyl peroxide had much higher toxicity than resveratrol, which may explain why benzoyl peroxide can cause skin irritation.

The researchers point out, however, that this toxicity reduced when both resveratrol and benzoyl peroxide were combined, indicating that both of the compounds together could treat acne more effectively but produce fewer side effects.

The findings, the researchers say, may even lead to new acne treatments. "We hope that our findings lead to a new class of acne therapies that center on antioxidants such as resveratrol," says Dr. Taylor.

The researchers note that further research is warranted to better determine how the two compounds work together to kill acne bacteria, and their findings will need to be validated in patients with acne.

Medical News Today recently reported in a study presented at the 5th American Society for Microbiology Conference on Beneficial Microbes in Washington, DC, claiming a certain bacteria could help treat acne and other skin disorders.

A number of studies have also hailed resveratrol for other benefits. In 2012, MNT reported on a study claimingresveratrol has anti-aging properties, while researchers of a more recent study claim to have identified why resveratrol may prevent heart disease and cancer.

Written by 

Copyright: Medical News Today

Not to be reproduced without permission.

Selena Gomez Hires Kris Jenner As New Manager, Receives Plastic Surgery Tips From Reality Star

Sun, 10/19/2014


Selena Gomez

By Pooja Bhagat | October 19, 2014 7:06 PM EST

Selena Gomez is told lately to prepare herself and increase her stamina for possible future changes in her life. This piece of advice was given by none other than her new manager Kris Jenner.

OK Magazine told that the reality star mother and ex-wife of Bruce Jenner is set to do a major makeover on Gomez. She has registered the 22-year-old pretty actress to a grueling boot camp to harden her body. As per a source, Jenner wants Kate Hudson-like abs for Gomez as well.

She's giving her tips and advice on everything from surgery to body hair and Gomez is surely impressed, as revealed by the insider of the magazine.

The mother of Kim Kardashian is also advocating the importance of plastic surgery to her new client. Jenner already manages the career and work of her children Kylie and Kendal Jenner along with Kourtney, Rob, Khloe and Kim Kardashian.

Jenner met her client during the Paris Fashion Week last month and Gomez was evidently impressed by her managing skills. Gomez badly needed someone to take control of her work as she fired her as her manager a few months ago.

Recently separated from Justin Bieber, the actress and singer was in a complete mess, as declared by the report in OK Magazine. She needed someone to anchor her work and lifestyle, and zeroed in on Jenner after meeting her coincidentally.

Jenner is also taking her new job quite seriously and enthusiastically. She is said to be dedicated to mentor Gomez like she does her own children. Her few of the initial advices to the teenage sweetheart is improving her fitness level and considering the option of plastic or cosmetic surgery. In fact, Jenner got the star registered in the same boot camp attended by Kim Kardashian.

In the meantime, critics are raising their concern over Gomez's decision to let Jenner manage her career for her. For starters, Jenner comes with a hefty price tag as she pockets 10 per cent of her client's total profit. Business 2 Community has raised concern as how Gomez will be benefitted by such a tie-up or whether she will be pushed into another zone.

In the meantime, the Daily Caller has declared Gomez as the hottest and the most sought after star on the internet this week.

To contact the editor, e-mail: editor@ibtimes.com

Researchers find why depression and aging linked to increased disease risk

Sun, 10/19/2014

Psychological stress and stress-related psychiatric disorders are associated with increased risk for aging-related diseases, but the molecular mechanisms underlying this relation are unknown. Understanding these mechanisms may contribute to the development of targeted preventive strategies and new or improved treatments for these devastating diseases. This work is presented at the European College of Neuropsychopharmacology congress in Berlin.

Now an international group of researchers from Germany and the US has found that both ageing and  are associated with changes in the FKBP5 gene. Genes can be regulated by the addition or removal of methyl (CH3) groups to an area of the gene. The researchers found that ageing can decrease this methylation process, causing the FKBP5 gene to be overexpressed. They also found that when someone is depressed, this demethylation process is accelerated even further.

In a second finding they found that this increased FKBP5 expression is associated with increases in biochemical markers of inflammation and .

According to lead researcher, Dr Anthony Zannas (Max Planck Institute of Psychiatry, Munich):

"We found that both aging and depression seem to lead to changes in how DNA is processed, and that this can control the expression of genes that regulate how we respond to stress. These changes are associated with increased inflammation, and we believe that this may lead to the increased risk for several aging-related diseases, such as cardiovascular diseases and neuropsychiatric disorders, that has been observed in chronically stressed and depressed individuals.

Our work shows that risk for aging-related diseases could be conferred by  of stress-related genes and resultant increases in the expression of inflammation markers. It's too early to say that we are seeing a cause and effect, so we need to confirm the findings by using larger samples and uncover the mechanisms using animal models. If we can do that, we may have the opportunity to develop tests for age-related diseases and new ways to prevent the harmful effects of stress".

The FKBP5 gene is found on chromosome 6 in humans. It codes the FK506 binding protein 5, also known as FKBP5. This protein is known to play a role in stress responses, immune regulation and basic cellular processes involving protein folding.

Commenting on the work for the ECNP, Professor Bill Deakin (Manchester) said:

"There is a growing realisation that depression is one expression of a set of vulnerabilities for a range of disorders associated with age including obesity, diabetes, cerebro-vascular  and dementia. Zannas and colleagues are now beginning to unpick some of the first  of the shared risk. The focus is on FKBP5 a protein transcription factor that regulates several genes relevant to depression (via stress hormones) and to disorders such as Alzheimer's disease.

Experiencing trauma in childhood and ageing have long-term influences on activity of the gene for FKBP5. This epigenetic regulation is abnormal in people with depression. It is early days and these findings need to be confirmed in definitively large populations. Nevertheless, the results point the way to finding molecular subtypes of depression with specific treatments targeted on transcription factors and ".

Explore further: DNA modifications measured in blood signal related changes in the brain

Provided by European College of Neuropsychopharmacology

FOREVER BEAUTIFUL: Banish painful pimples

Sun, 10/19/2014


PUBLISHED: 16:58 EST, 12 October 2014 | UPDATED: 10:47 EST, 13 October 2014

Every Monday, Elsa answers readers' big beauty queries and presents the best buys to perk up your week... 

I’m 53 and have had acne on and off since my mid-20s. It still flares up — usually when my hormones fluctuate every month. My skin is oily, but when I have a facial I’m told my skin is dehydrated, which confuses me. Should I use products to dry up the oil or to put moisture into my skin?

Caroline, Preston.

Acne isn't just a problem for teenagers and usually flares up when your hormones are fluctuating


Acne isn't just a problem for teenagers and usually flares up when your hormones are fluctuating


Up to half of all women suffer from acne at some point in their lives. This can be due to a number of factors including hormones, skin type, genes and diet. Often the cause of breakouts is unknown, so prevention can be difficult.

However, using products that are right for your skin can regulate your complexion, minimising breakouts and the chance of scarring


In the past few years, Dr Stefanie Williams, dermatologist and medical director at European Dermatology, London, has noticed a sharp rise in adult acne among her patients.

Effaclar Anti-Blemish System

La Roche Posay Effaclar Cleansing System

‘We see more and more women into their 40s and 50s with adult acne,’ she says. ‘That’s particularly frustrating, as you’re then faced not only with spots, but also the beginnings of lines and wrinkles. The first question is whether you really have acne. There is a condition called rosacea that can look very similar and is common in middle-aged women.

‘Often these women had acne in their teens, then “graduate” to rosacea. The best thing is to see a dermatologist to get a diagnosis and prescription treatment.

‘If it is confirmed you have acne, I can recommend over-the- counter products: La Roche-Posay Effaclar 3-Step Anti-Blemish System £32.50,and Eau Thermale Avene Triacneal, £23 (both from Boots).

‘Wash your face with La Roche Posay Physiological Cleansing Gel, £12 (Boots).

‘Despite being told your skin is dehydrated, you shouldn’t use heavy moisturisers. Also avoid oil-based or creamy cleansers.’

Sally Penford, education manager of the International Dermal Institute, explains how skin can be oily and dehydrated.

‘Acne produces more oil than average skin and this, coupled with a build-up of dead cells and bacteria in the follicles, causes blackheads and breakouts.

‘However, our environment and skincare regimes can also leach essential moisture from the skin and cause dehydration.

Clarins Lotus Face Treatment Oil

Clarins Lotus Face Treatment Oil

‘You need to find a water- soluble cleanser that will deep-clean and treat the excess oil while maintaining the skin’s balance and keeping moisture levels intact. Once skin is cleansed, I recommend a hydroxy acid intensive booster that contains glycolic or lactic acid to improve the texture and tone of the skin.

‘Finally, apply a moisturiser that has antibacterial and healing effects while also hydrating skin and protecting it from UV.

‘And for monthly hormonal breakouts, keep a concentrated spot treatment to hand with ingredients such as sulphur, niacinamide and tea tree oil.’

Marie McKeever, head of training at Clarins, says while there’s a temptation to ‘dry’ oily skin, slowing oil-producing glands in the skin is the answer.

‘Clarins Lotus Face Treatment Oil, £32 (clarins.co.uk) is perfect for oily skin. The ingredients slow secretions of the sebaceous glands and they gradually become less active. Over time, there will be fewer spots and blackheads.’

Are you identical twins aged over 40 who would like to take part in a unique experiment for this column? Write to me at elsa@dailymail.co.uk, enclosing a recent picture.

What is the best skin care regimen to prevent acne


Treats to make your Monday marvellous

Though the days are getting shorter, you can still inject some welcome springtime in your beauty routine.

The new White Lily & Damask Rose range from Sanctuary Spa is scented with subtle florals that not only smell great, but can also lift your mood.

White Lily & Damask Rose range, Sanctuary Spa
Australian Bodycare Purifying Clay Mask

White Lily & Damask Rose range from Sanctuary Spa (left) and Australian Bodycare Purifying Clay Mask (right)

Choose from body wash, £5.50, body scrub, £5.50, hand wash, £4.50, and body lotion, £5.50 (Boots), for softer skin with a delicious feminine scent.

One of the benefits of a facemask is the feeling of deep cleanness.

The Australian Bodycare Purifying Clay Mask, £16.50 (australianbodycare.co.uk) soaks deep into the pores, getting rid of impurities.

It uses tea tree oil to give a deep cleanse, macadamia oil to soothe, papaya extract to exfoliate and minerals to purify. If you like that clean feel, you’ll love this.

Katie Price Plans Her SEVENTH Boob Job After Moving House Following Kieran Hayler's Affair

Sun, 10/19/2014

She hopes to forget the painful cheating memories by moving next door.

By Stephanie Soteriou |

Katie Price has certainly been a busy bee of late.

Now that she has upped and moved from the house where her husband, Kieran Hayler, cheated on her with two of her best friends, Katie has revealed plans for a seventh, SEVENTH, boob job.


Katie Price has moved house following Kieran's affair. Copyright [Wenn]

Katie Price has moved house following Kieran's affair. Copyright [Wenn]

First of all, the 36-year-old has officially left the house which was apparently full of painful memories, but she hasn't exactly gone far...

In fact, she's only gone and bought the house next door!

At just thirty metres away you might wonder whether that is still a tad too close to the scene of Kieran's crime for Katie to well and truly move on, however, at least she won't have to go anywhere near the dastardly stables where her husband did the dirty with Jane Poutney of West Chiltington, and they were the real trouble for her.

Katie and Jane (far left) had been besties for years. Copyright [Twitter]

Katie and Jane (far left) had been besties for years. Copyright [Twitter]

A source had previously told The Sun: "The stables hold very painful memories for her and she has been visiting them less and less.

"She wants a fresh start and to forget what happened, this sale will be part of that."

But thankfully Katie isn't going without, with her new lavish property also boasting stables as well as tennis courts and 12 acres of land.

Which, if you can believe it, is actually a downsize from her old home, which had a whopping 53 acres.

Katie was obviously happy to keep it casual this time around.

Katie Price wants ANOTHER boob job. Copyright [Rex]Katie Price wants ANOTHER boob job. Copyright [Rex]

Speaking of keeping it casual, the former glamour model has also revealed the details of her 2014 Christmas present to herself, and it's a good'un.

Katie revealed: "I’m getting my boobs done again - my Christmas pressie to myself. You heard it here first.

"Two years of pregnancy have made them a little saggy. When I’m an old lady and I die I’ll have the perfect boobs. Everything else will have sagged but my boobs."

Well, what old lady doesn't want to die with perfect boobs?

Katie gave birth to her fifth child, Bunny, back in August which was almost exactly a year after she gave birth to son, Jett Riveria.

Katie with baby Bunny. Copyright: [YouGossip]Katie with baby Bunny. Copyright: [YouGossip]

The star also has two children, 9-year-old Junior and 7-year-old Princess, with her ex-husband Peter Andre, and 12-year-old Harvey with footballer Dwight Yorke.

The mum-of-five gave us some serious body envy just last week when she flashed her super-toned tumjust two months after giving birth to her second daughter.

Katie credits loverat hubby Kieran for her dramatic post-baby weight loss, saying that his skills in the kitchen have resulted in her snapping back into her size 8 clothes in no time.

Katie Price showed off her VERY toned tum just a few months after giving birth. Copyright [Splash News]Katie Price showed off her VERY toned tum just a few months after giving birth. Copyright [Splash News]

She told the Daily Mail: "I believe in eating healthily and I eat a lot better now. Kieran makes delicious salads for me, I never knew how to make them before and they always tasted so bland but he is really into health and fitness so knows what works."

Who knew that sleeping with your spouse's best friends could be so simply resolved with a good salad and new house?

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